Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy
Phase 1
40
about 1.6 years
18–60
1 site in MD
What this study is about
Researchers are testing if a drug called mangafodipir can be safely used to show areas affected by epilepsy on an MRI. The trial will involve adults with epilepsy who have not responded to medication, and it will last for about 590 days.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Mangafodipir
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
mangafodipir
Primary: evaluation of the utility of MEMRI and/or DCE-MRI in identifying focal BBBD in the seizure onset zone identified by standard clinical, EEG, and imaging studies, and the homologous contralateral region.
Neurology