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Study details
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TAPUR Trial

American Society of Clinical Oncology
NCT IDNCT02693535ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

4,200

Study length

about 13 years

Ages

12+

Locations

174 sites in AL, AZ, CA +25

What this study is about

This trial is testing different treatments for advanced cancer. The goal is to learn from real-world prescribing practices and predict which patients will benefit most from targeted therapies.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive Tucatinib plus Trastuzumab Subcutaneous (SC)
  • 2.Take Abemaciclib
  • 3.Take Atezolizumab and PHESGO
  • +3 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
OralInjection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

abemaciclib, atezolizumab, cobimetinib, dabrafenib, Antineoplastic Agent [TC] (HER2/Neu/cerbB2 Antagonists), futibatinib, ipilimumab (Immune checkpoint inhibitor; blocks CTLA-4 on T cells), nivolumab (Immune checkpoint inhibitor; blocks PD-1 receptor on T cells)

Drug routes

oral (Oral Tablet), injection (Injection), oral (Oral Capsule), infusion, oral, injection, intravenous

Endpoints

Primary: Objective Response Rate defined as % of participants in a cohort with complete or partial response or with stable disease according to standard response criteria

Secondary: Overall survival (OS)

Body systems

Oncology