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Study details
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Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOA

Northwell Health
NCT IDNCT02800486ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

37

Study length

about 11 years

Ages

18+

Locations

1 site in NY

What this study is about

This trial is testing a treatment with intra-arterial Cetuximab and reirradiation for patients whose brain cancer has returned after other treatments. The goal is to see if this approach can help prevent the cancer from growing back.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive Hypofractionated re-irradiation
  • 2.Take Intra-arterial Cetuximab
  • 3.Take Intra-arterial Mannitol

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVInjection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

ALIMENTARY TRACT AND METABOLISM

Drug routes

injection (Injection)

Endpoints

Primary: Overall Survival (OS), Progression Free Survival (PFS)

Secondary: Composite overall response rate (CORR) through the Response Evaluation Criteria In Solid Tumors (RECIST), Toxicities graded according to the NCI Common Toxicity Criteria (CTCAE) version 4.03

Procedures

radiation

Body systems

Oncology