Gene Transfer Trial for Cancer
Phase 1/2
124
about 11 years
18–72
1 site in MD
What this study is about
This trial is testing a new way to treat cancer by modifying blood cells with a special gene. Researchers are giving these modified cells back to patients who have CD70-expressing cancers like breast, melanoma, ovarian, pancreatic, or renal cell cancer. The goal is to see if this treatment can safely shrink tumors and determine its safety.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive Anti-hCD70 CAR transduced PBL
- 2.Take Aldesleukin
- 3.Take Cyclophosphamide
- +1 more
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
aldesleukin, cyclophosphamide (Alkylating chemotherapy; crosslinks DNA strands), fludarabine
infusion
Primary: Frequency and severity of treatment-related adverse events, Response rate
Secondary: Frequency and severity of treatment-related adverse events
Oncology