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Study details
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Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma

Northwell Health
NCT IDNCT02861898ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

33

Study length

about 12 years

Ages

18+

Locations

1 site in NY

What this study is about

This trial is testing a treatment called super-selective intra-arterial repeated infusion of cetuximab (CTX) in people with newly diagnosed glioblastoma. The treatment will be given after disrupting the blood-brain barrier, along with standard chemotherapy and radiation therapy (STUPP protocol).

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Intra-arterial Cetuximab
  • 2.Take Intra-arterial Mannitol

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVInjection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

ALIMENTARY TRACT AND METABOLISM

Drug routes

injection (Injection)

Endpoints

Primary: Overall Survival (OS), Progression Free Survival (PFS)

Secondary: Composite overall response rate (CORR) through the Response Assessment in Neuro-Oncology (RANO), Toxicities graded according to the NCI Common Toxicity Criteria (CTCAE) version 4.03

Body systems

Oncology