Skip to content
Study details
Enrolling now

Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
NCT IDNCT03184038ClinicalTrials.gov data as of Apr 2026
Target enrollment

90

Study length

about 9.6 years

Ages

18+

Locations

2 sites in NJ, PA

What this study is about

This trial is testing how radiosurgery affects the brain function of patients with multiple brain metastases. It compares the effects of stereotactic body radiation therapy (SBRT) and stereotactic radiosurgery (SRS) on cognitive function and quality of life in these patients.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Quality-of-Life Assessment
  • 2.Receive Stereotactic Body Radiation Therapy
  • 3.Receive Stereotactic Radiosurgery
  • +1 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: Change in symptom burden as measured by the MD Anderson Symptom Inventory- Brain Tumor Module (MDASI-BT), Incidence of adverse events graded according to the Common Terminology Criteria for Adverse Events version 5.0, Local control as measured by magnetic resonance imaging, Overall survival (OS), Progression free survival (PFS), Quality adjusted survival and health outcomes as measured by the European Quality of Life Five Dimension Five Level scale questionnaire (EQ-5D-5L)

Procedures

radiation