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Study details
Enrolling now

Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM

Northwell Health
NCT IDNCT03213002ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

67

Study length

about 10 years

Ages

18–74

Locations

1 site in NY

What this study is about

This trial is testing a treatment with capecitabine and temozolomide for newly diagnosed glioblastoma multiforme (GBM). The goal is to determine if this combination is safe and effective, comparing it to standard temozolomide alone.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Capecitabine
  • 2.Take Temozolomide

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
OralInjection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

capecitabine, temozolomide

Drug routes

oral (Oral Tablet), injection, intravenous

Endpoints

Primary: Overall Survival (OS), Progression-free survival (PFS)

Secondary: Composite overall response rate (CORR) through the Response Evaluation Criteria In Solid Tumors (RECIST), Toxicities will be tabulated and graded according to the NCI Common Toxicity Criteria (CTCAE) version 4.03.

Body systems

Neurology, Oncology