Skip to content
Study details
Enrolling now

Azacitidine and Enasidenib in Treating Patients With IDH2-Mutant Myelodysplastic Syndrome

M.D. Anderson Cancer Center
NCT IDNCT03383575ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

63

Study length

about 9.1 years

Ages

12+

Locations

3 sites in MD, OH, TX

What this study is about

This trial is testing azacitidine and enasidenib as a treatment for patients with IDH2-mutant myelodysplastic syndrome. The goal is to assess the safety and effectiveness of these medications in stopping cancer cell growth.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Quality-of-Life Assessment
  • 2.Take Azacitidine
  • 3.Take Enasidenib

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVsubcutaneous

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

azacitidine, enasidenib

Drug routes

injection, subcutaneous, oral (Oral Tablet)

Endpoints

Primary: Incidence of adverse events, Overall response rate

Secondary: Event-free survival (EFS), Overall survival (OS)

Body systems

Musculoskeletal, Oncology