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Study details
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Pioglitazone Trial for Kidney Disease

The University of Texas at Arlington
NCT IDNCT03471117ClinicalTrials.gov data as of Apr 2026
Phase

Phase 4

Target enrollment

28

Study length

about 8 years

Ages

35–70

Locations

2 sites in TX

What this study is about

This trial is testing whether a short-term treatment with pioglitazone can reduce sympathetic nerve activity in people with chronic kidney disease. The goal is to see if pioglitazone helps lower the risk of cardiovascular problems and death in these patients.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Placebo
  • 2.Take Pioglitazone

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

pioglitazone (Thiazolidinedione; improves insulin sensitivity by activating PPAR-gamma)

Drug routes

oral (Oral Tablet)

Body systems

Renal