Dexrazoxane Hydrochloride to Prevent Heart Problems from Chemotherapy
Phase 2
100
about 9.3 years
12+
1 site in TX
What this study is about
This trial is testing whether dexrazoxane hydrochloride can help prevent heart problems caused by chemotherapy in people with blood cancers. The treatment involves taking dexrazoxane hydrochloride along with other chemotherapy drugs like cladribine, idarubicin, cytarabine, and gemtuzumab ozogamicin.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Cladribine
- 2.Take Cytarabine
- 3.Take Dexrazoxane Hydrochloride
- +2 more
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
cladribine, cytarabine, Cardiovascular Agent [TC] (Chelating Activity), gemtuzumab ozogamicin, idarubicin
injection, intravenous, injection (Injection), infusion
Secondary: Complete remission (CR) /complete remission with incomplete blood count recovery (CRi) rates (Cohorts 1-3), Event-free survival (Cohorts 1-3), Incidence of adverse events, Incidence of cardiac symptoms, Overall response (Cohorts 1-3), Overall survival (Cohorts 1-3), Recurrence-free survival
Oncology, Musculoskeletal