Edetate Calcium Disodium or Succimer for Leukemia Treatment
Phase 1
58
about 8.6 years
1+
1 site in TX
What this study is about
This trial is testing edetate calcium disodium or succimer in patients with acute myeloid leukemia or myelodysplastic syndrome undergoing chemotherapy. The goal is to determine the best dose and side effects of these treatments, which may help lower metals in the body and improve response to chemotherapy.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Multivitamin
- 2.Take Edetate Calcium Disodium
- 3.Take Succimer
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Antidotes, Deterrents, and Toxicologic Agents (Chelating Activity), Antidotes, Deterrents, and Toxicologic Agents (Lead Chelating Activity)
oral (Oral Capsule)
Primary: Incidence of adverse events, Maximum tolerated doses (MTD) of edetate calcium disodium (Ca-EDTA) and succimer (DMSA) (Phase 1 dose escalation)
Oncology