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Study details
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Etelcalcetide Trial in Children with Kidney Disease

Amgen
NCT IDNCT03633708ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

56

Study length

about 9.8 years

Ages

0–18

Locations

10 sites in CA, CO, MO +6

What this study is about

Researchers are testing a treatment called Etelcalcetide in children with kidney disease and high parathyroid hormone levels. This treatment aims to help manage these conditions, which can cause bone problems and other complications. The trial will last for about 3 years.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Etelcalcetide

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IV

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

etelcalcetide

Drug routes

injection (Injection)

Endpoints

Primary: Percentage Change from Baseline in Mean iPTH During the EAP

Secondary: Change from Baseline in Diastolic Blood Pressure, Change from Baseline in Heart Rate, Change from Baseline in Systolic Blood Pressure, Change in Weight, Maximum Serum Concentration (Cmax) of Etelcalcetide, Mean Change from Baseline in Predialysis iPTH from Baseline during the EAP, Number of Participants who Experienced Adverse Events (AEs), Percentage Change from Baseline in Corrected Total Serum Ca from Baseline During the EAP

Body systems

Renal