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Study details
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ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease

InSightec
NCT IDNCT03671889ClinicalTrials.gov data as of Apr 2026
Target enrollment

150

Study length

about 7.3 years

Ages

50–85

Locations

10 sites in FL, NY, OH +2

What this study is about

This trial is testing a device to disrupt the blood-brain barrier in people with probable Alzheimer's disease. The goal is to evaluate if this device is safe and effective.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Use Blood Brain Barrier (BBB) Disruption

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Standard assignment

Assignment is predetermined by the study protocol.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Device and procedure related adverse events

Body systems

Neurology