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Study details
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4-Aminopyridine Treatment for Nerve Injury

John Elfar
NCT IDNCT03701581ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2/3

Target enrollment

70

Study length

about 7.6 years

Ages

45–75

Sex

Male only

Locations

2 sites in AZ, NY

What this study is about

This trial is testing whether 4-aminopyridine (4-AP) can help with recovery after nerve injuries. The treatment will be compared to a placebo.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Placebo
  • 2.Take 4-Aminopyridine

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

fampridine

Endpoints

Primary: Michigan Incontinence Sympton Index (M-ISI) (change over time)

Body systems

Oncology