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Study details
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Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea

Wayne State University
NCT IDNCT03736382ClinicalTrials.gov data as of Apr 2026
Target enrollment

40

Study length

about 7 years

Ages

18–60

Locations

2 sites in MI

What this study is about

This trial is testing if repeated daily exposure to mild intermittent hypoxia, combined with CPAP, can improve sleep apnea. The goal is to see if this approach helps reduce the need for CPAP and improves overall health.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Continuous positive airway pressure (CPAP)
  • 2.Mild intermittent hypoxia
  • 3.Sham protocol

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Change in blood pressure measured during quiet wakefulness over the 24 hour period following mild intermittent hypoxia and sham protocol

Secondary: Change in beat to beat measures of blood pressure following mild intermittent hypoxia and sham protocol, Change in blood pressure measured during sleep over 24 hours following mild intermittent hypoxia and sham protocol

Devices

therapeutic

Body systems

Neurology