Skip to content
Study details
Enrolling now

A Study of LB-100 in Patients With Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS)

Lixte Biotechnology Holdings, Inc.
NCT IDNCT03886662ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

47

Study length

about 2.3 years

Ages

18+

Locations

1 site in FL

What this study is about

Researchers are testing the safety and efficacy of LB-100, a medication, for patients with low or intermediate-1 risk myelodysplastic syndromes. The trial will involve administering LB-100 intravenously over 120 minutes in two phases: an escalating dose phase to determine a safe dose and a dose-finding phase to assess the drug's efficacy and safety.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take LB-100

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: For Phase 2 - Best overall response rate of patients to the study treatment as a measure of efficacy of LB-100 study drug, For Phase Ib - Number of patients with adverse events related to the study treatment as a measure of safety and tolerability of LB-100 study drug