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Study details
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Effects of Dronabinol in Opioid Maintained Patients

Yale University
NCT IDNCT04025359ClinicalTrials.gov data as of Apr 2026
Phase

EARLY_PHASE1

Target enrollment

36

Study length

about 7.3 years

Ages

18–70

Locations

1 site in CT

What this study is about

This trial is testing if dronabinol helps people who are currently taking opioids for chronic pain. Participants will receive either dronabinol or a placebo, and their opioid-related outcomes will be measured using various tests like pain sensitivity measurements, cognitive assessments, and urine toxicology testing.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Dronabinol
  • 2.Take Placebo

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

dronabinol

Drug routes

oral (Oral Capsule)

Endpoints

Primary: Pain sensitivity, measured by the Cold Pressor Test (CPT)., Pain sensitivity, measured by the Short form of the McGill Pain Questionnaire (SF-MPQ).