Study details
Enrolling now
Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma
St. Jude Children's Research Hospital
NCT IDNCT04065776ClinicalTrials.gov data as of Apr 2026
Target enrollment
74
Study length
about 8.9 years
Ages
6–21
Locations
2 sites in MN, TN
What this study is about
This trial is testing if using proton therapy to avoid radiation to the hippocampus can be a safe and effective treatment for certain types of low-grade brain tumors. The goal is to see how well this approach works, including measuring memory function and overall cognitive performance over time.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive Hippocampal-avoidance proton therapy
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Standard
How treatment is administered
Treatment Assignment
All receive treatment
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Endpoints
Secondary: EFS of LGGs treated with HA