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Study details
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LITT Followed by Hypofractionated RT for Recurrent Gliomas

University of Maryland, Baltimore
NCT IDNCT04181684ClinicalTrials.gov data as of Apr 2026
Target enrollment

32

Study length

about 7 years

Ages

22+

Locations

4 sites in MD

What this study is about

This trial is testing whether using Laser Interstitial Thermal Therapy (LITT) followed by hypofractionated radiation therapy can be a treatment option for patients with recurrent gliomas. LITT offers an alternative to surgery, and obtaining a tissue diagnosis before starting radiation therapy is another benefit of this approach.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive Hypo-Fractionated Radiation Therapy
  • 2.Use Procedure: LITT

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Adverse Events

Secondary: 1-year overall survival, Median overall survival, Median progression-free survival, Overall response rate, Progression-free survival at 6 months, Quality of Life before, during, and after treatment

Procedures

radiation

Body systems

Oncology