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Study details
Enrolling now

Lung Cancer Treatment Trial

Genentech, Inc.
NCT IDNCT04302025ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

99

Study length

about 9.6 years

Ages

18+

Locations

38 sites in CA, CO, CT +15

What this study is about

This trial is testing different treatments for lung cancer. It includes drugs, surgery (resection), and radiation therapy (SBRT). The goal is to find the best treatment option based on specific characteristics of each patient's tumor.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Alectinib
  • 2.Take Atezolizumab
  • 3.Take Chemotherapy
  • +3 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
OralInjection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

alectinib, atezolizumab, cobimetinib, entrectinib, pralsetinib, vemurafenib

Drug routes

oral (Oral Capsule), injection (Injection), oral (Oral Tablet), oral

Endpoints

Primary: KRAS Cohort: Percentage of Participants With 3-5 Grade Adverse Events (AEs), KRAS Cohort: Percentage of Participants Without Delays of Surgery due to Treatment-related Adverse Events as Reported by the Investigator

Secondary: Circulating tumor DNA (ctDNA) Clearance Rate, Disease-free Survival (DFS), Event-free Survival (EFS), Investigator-assessed Response Objective Response Rate (ORR) per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST v1.1), Overall Survival (OS), Percentage of Participants With Adverse Events (AEs)

Procedures

surgery

Body systems

Oncology