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Study details
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EMPOWER Trial

University of Southern California
NCT IDNCT04333706ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

65

Study length

about 6.9 years

Ages

18–99

Locations

3 sites in CA, FL

What this study is about

This trial is testing a new treatment called Sarilumab plus Capecitabine in people with triple-negative breast cancer. The goal is to see if it can help eliminate minimal residual disease (MRD) after standard treatments, potentially improving survival and cure rates for this aggressive type of breast cancer.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Capecitabine
  • 2.Take Sarilumab 150mg or 200 mg plus Capecitabine
  • 3.Take Sarilumab 150mg plus Capecitabine

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

capecitabine, sarilumab, ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS

Drug routes

oral (Oral Tablet)

Endpoints

Primary: Phase I: Dose-limiting toxicity (DLT), Phase I: Maximum Tolerated Dose (MTD)

Body systems

Oncology