Lofexidine and Buprenorphine for PTSD and Opioid Relapse
Phase 2
120
about 4.8 years
18–70
2 sites in TX
What this study is about
Researchers are testing if lofexidine, taken with buprenorphine, helps reduce symptoms of both opioid use disorder and post-traumatic stress disorder in veterans. The trial will compare the safety and effectiveness of buprenorphine alone versus buprenorphine plus lofexidine.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Lofexidine
- 2.Take Placebo oral tablet
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
lofexidine
oral (Oral Tablet), oral
Primary: Opioid Use, PTSD Symptoms (Checklist)
Secondary: PTSD Symptoms
Psychiatry / Mental Health