EBRT and HDR Brachytherapy for Unfavorable-intermediate, High, and Very High-risk Prostate Cancer
Phase 2
60
about 8.4 years
18+
Male only
1 site in VA
What this study is about
Researchers are testing if a combination of androgen deprivation therapy (ADT), MRI guided high dose radiation (HDR) brachytherapy treatment (internal radiation implant procedure) and external beam radiation therapy (EBRT) treatments leads to less side effects. The trial also looks at patient outcomes, quality of life, and overall survival for patients receiving this treatment.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive External Beam Radiation
- 2.Receive HDR Brachytherapy
- 3.Take Androgen Deprivation Therapy
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
hormone therapy
Primary: Compare GU toxicity rate to the rate published in the ASCENDE-RT trial
Secondary: Describe impact of treatment on quality of life, Estimate GI and sexual toxicity, Estimate freedom from biochemical failure (RFS), Estimate the prevalence of grade 3 or greater GU toxicity
radiation
Oncology