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Study details
Enrolling now

Azacitidine and Quizartinib for Blood Cancer

M.D. Anderson Cancer Center
NCT IDNCT04493138ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

58

Study length

about 7.4 years

Ages

18+

Locations

1 site in TX

What this study is about

This trial is testing the safety and best dose of quizartinib when combined with azacitidine in people with myelodysplastic syndrome or myelodysplastic/myeloproliferative neoplasm who have FLT3 or CBL mutations. The goal is to see if this combination treatment can help control these blood cancers.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Azacitidine
  • 2.Take Quizartinib

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVsubcutaneous

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

azacitidine, quizartinib

Drug routes

injection, subcutaneous, oral (Oral Tablet)

Endpoints

Primary: Duration of response, Incidence of adverse events (AEs), Overall response rate, Overall survival, Relapse-free survival

Body systems

Oncology