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Study details
Enrolling now

CPX-351 and Ivosidenib for Leukemia Treatment

M.D. Anderson Cancer Center
NCT IDNCT04493164ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

30

Study length

about 5.4 years

Ages

18+

Locations

1 site in TX

What this study is about

This trial is testing a treatment with CPX-351 and ivosidenib to see if it helps people with acute myeloid leukemia or high-risk myelodysplastic syndrome that has an IDH1 mutation. The goal is also to learn about the safety of this combination.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Ivosidenib
  • 2.Take Liposome-encapsulated Daunorubicin-Cytarabine

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
OralInjection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

ivosidenib

Drug routes

oral (Oral Tablet), injection (Injection)

Endpoints

Primary: Overall response rate (ORR)

Secondary: Duration of response, Event-free survival, Incidence of adverse events, Overall survival

Body systems

Oncology