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Study details
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Verteporfin for Recurrent High Grade EGFR-Mutated Glioblastoma

Emory University
NCT IDNCT04590664ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

24

Study length

about 4.6 years

Ages

18+

Locations

1 site in GA

What this study is about

This trial is testing the safety and effectiveness of verteporfin, a drug called Visudyne, in treating recurrent high grade EGFR-mutated glioblastoma. Verteporfin is being used as a treatment to kill tumor cells that may be sensitive to this medication.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Verteporfin

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Injection / IVInjection / IV

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

verteporfin

Drug routes

injection, intravenous

Endpoints

Primary: Incidence of adverse events (Phase I), Overall survival (Phase II), Progression free survival (PFS) (Phase II), Response rate (RR) (Phase II)

Secondary: Incidence of adverse events (Phase II), Overall survival (Phase I), PFS (Phase I)

Body systems

Oncology