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Study details
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Rapamycin Trial for Memory Problems

The University of Texas Health Science Center at San Antonio
NCT IDNCT04629495ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

40

Study length

about 4.6 years

Ages

55–89

Locations

1 site in TX

What this study is about

This trial is testing the safety of rapamycin, a drug, in older adults with memory problems. The goal is to see if this treatment can be safely given and how well it works over 1693 days.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Placebo
  • 2.Take Rapamycin

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

sirolimus

Endpoints

Primary: Number of adverse events

Secondary: Change in Functional status, Change in Gait Speed, Change in Grip Strength, Change in Neuropsychiatric symptoms

Body systems

Neurology