Dual Frequency Stimulation in Parkinson's Disease
10
about 3.7 years
18+
1 site in CA
What this study is about
This trial is testing a new way to treat Parkinson's disease using deep brain stimulation. It involves stimulating both the dorsal and ventral regions of the subthalamic nucleus with different frequencies. The goal is to see if this approach can improve motor symptoms while minimizing cognitive side effects.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Use Deep brain stimulation
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Primary: Mean Change from Baseline in Cognitive Performance Scores on the Montreal Cognitive Assessment - Blind (MoCA), Mean Change from Baseline in Depression Scores on the CES-D Short Version (CES-D-R10), Mean Change from Baseline in Depression Scores on the Center for Epidemiologic Studies Depression Scale (CES-D), Mean Change from Baseline in Impulsiveness Scores on the Barratt Impulsiveness Scale (BIS-11), Mean Change from Baseline in Motor and Non-Motor Aspects of Daily Living Scores on Parts I and II of the MDS-UPDRS, Mean Change from Baseline in Movement Scores on Part III of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS), Mean Change from Baseline in Neuropsychiatric Inventory (NPI)
Secondary: Mean Change from Baseline in Decision-Making Scores on Probabilistic Gambling Task, Mean Change from Baseline in Inter-Temporal Choice Scores on a Temporal Discounting Task, Mean Change from Baseline in Verbal Fluency Scores on Word Generation Task
implantable
Neurology