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Study details
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Opioid-Free Orthopaedics Trial

Emory University
NCT IDNCT04659317ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

80

Study length

about 8.1 years

Ages

18+

Locations

3 sites in GA

What this study is about

This trial is testing a new way to manage pain after orthopedic surgery that doesn't involve opioids. The goal is to see if this approach can reduce or eliminate the need for opioid medications in patients recovering from these procedures.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Oxycodone 5 mg Oral Tablet
  • 2.Take Placebo oral tablet

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
OralOral

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

oxycodone (Opioid; binds mu-opioid receptors for pain relief)

Drug routes

oral

Endpoints

Primary: Change in Pain (VAS) Score

Secondary: Change in European Quality of Life 5 dimension (EQ-5D), Length of stay postoperative, Number of complications