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Study details
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LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)

University of Maryland, Baltimore
NCT IDNCT04699773ClinicalTrials.gov data as of Apr 2026
Target enrollment

32

Study length

about 6.9 years

Ages

18+

Locations

5 sites in MD

What this study is about

Researchers are testing whether Laser Interstitial Thermal Therapy (LITT) followed by hypofractionated radiation therapy can be a treatment option for newly diagnosed gliomas. The trial will involve adults with these types of brain tumors and aims to determine the best course of treatment.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive Hypofractionated Radiation Therapy
  • 2.Undergo LITT

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Adverse Events

Secondary: 1-year overall survival, Median overall survival, Median progression-free survival, Overall response rate, Progression-free survival at 6 months, Quality of Life assessed by M.D. Anderson Symptom Inventory

Procedures

radiation

Body systems

Oncology