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Study details
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DEC-C Trial for MDS Patients After Transplant

Washington University School of Medicine
NCT IDNCT04742634ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1/2

Target enrollment

209

Study length

about 12 years

Ages

18–75

Locations

1 site in MO

What this study is about

This trial is testing if early treatment with DEC-C can help prevent relapse in people who have Myelodysplastic Syndromes (MDS) after a stem cell transplant. The goal is to see if detecting measurable residual disease and treating it with DEC-C improves outcomes.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take DEC-C
  • 2.Use MyeloSeq-HD

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Maximum tolerated dose (MTD) (Phase I only), Progression-free survival (PFS) (Phase II recommended dose only)

Secondary: Overall survival (OS) (Phase II recommended dose only)