High Dose Radiation vs. Whole Brain Radiation for Brain Cancer
Phase 3
200
about 9.1 years
18+
223 sites in AZ, CA, CO +27
What this study is about
This trial is testing if high dose radiation only to the brain cancer sites (stereotactic radiosurgery) is better than whole brain radiation that avoids the hippocampus, a memory area of the brain, at preventing loss of memory and thinking ability in people with lung cancer that has spread to the brain. The goal is to see if stereotactic radiosurgery causes fewer side effects related to memory and thinking compared to standard treatment (whole brain radiation plus memantine).
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Neurocognitive Assessment
- 2.Receive Stereotactic Radiosurgery
- 3.Receive Whole-Brain Radiotherapy
- +3 more
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You are randomly assigned, but you will know your treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Central Nervous System Agent (NMDA Receptor Antagonists)
oral (Oral Tablet)
Secondary: Incidence of adverse events, Overall survival, Symptom burden
diagnostic, imaging, radiation