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Study details
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Do Endotypes Predict Response and Sequelae in OSA Patients

University of California, San Diego
NCT IDNCT04875364ClinicalTrials.gov data as of Apr 2026
Phase

Phase 2

Target enrollment

200

Study length

about 6.4 years

Ages

21–65

Locations

1 site in CA

What this study is about

This trial is testing whether different underlying causes of Obstructive Sleep Apnea (OSA) predict how well people respond to treatment and what problems the disease might cause. The goal is to understand if knowing these 'endotypes' can help doctors choose the best way to treat each individual with OSA.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Supplemental Oxygen
  • 2.Take Eszopiclone
  • 3.Use Continuous Positive Airway Pressure (CPAP)

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

eszopiclone, VARIOUS

Drug routes

oral (Oral Tablet)

Endpoints

Secondary: Brief Pain Inventory (Short Form), Diastolic Blood Pressure, Epworth Sleepiness Scale (ESS), Functional Assessment of Chronic Illness Therapy Fatigue Scale (FACIT-F), Insomnia Severity Index (ISI), PROMIS (Patient-Reported Outcomes Measurement Information System) pain intensity, PROMIS (Patient-Reported Outcomes Measurement Information System) pain interference, Pittsburgh Sleep Quality Index (PSQI)

Devices

therapeutic