Repurposing Low-Dose Clonidine for PTSD in Veterans
Phase 3
32
about 2.8 years
18+
1 site in WI
What this study is about
This trial is testing whether low-dose clonidine helps veterans with PTSD. It compares clonidine to a placebo pill over 1034 days. The goal is to see if the treatment improves PTSD symptoms, including daytime and nighttime issues.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Placebo
- 2.Take Clonidine Pill
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
CARDIOVASCULAR SYSTEM
oral
Primary: Change from Baseline in Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) questions B2 and E6 at 6 weeks into phase, Change from Baseline in PTSD Checklist-Military Version (PCL-5) at 6 weeks into phase, Change from Baseline in Pittsburgh Sleep Quality Index (PSQI) at 6 weeks into phase
Secondary: Change from Baseline in Patient Health Questionnaire (PHQ9) at 6 weeks into phase, Change from Baseline in Sleep Diary at 6 weeks into phase, Change from Baseline in quality of life scale (Q-LES-Q-SF) at 6 weeks into phase
Psychiatry / Mental Health