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Study details
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Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety

Massachusetts General Hospital
NCT IDNCT04912531ClinicalTrials.gov data as of Apr 2026
Target enrollment

80

Study length

about 2.7 years

Ages

18+

Locations

1 site in MA

What this study is about

This trial is testing a new way to help reduce pain and anxiety after heart surgery. It uses virtual reality, smells, and other devices to try and make patients feel better instead of using opioids or benzodiazepines. The goal is to see if this approach works and can be used in the future.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Use Bedside Olfaction Device
  • 2.Use Essence Olfactory Necklace
  • 3.Use Virtual Realty using a Microsoft Hololens, Empatica HR wristband, and EEG

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: Change in Anxiety Score (State Trait Anxiety Inventory), Change in Pain Score (Visual Analogue Scale), Change in Quality of Life (The Functional Assessment of Cancer Therapy - General )(FACT-G), Change in Sleep Quality (Pittsburgh Sleep Quality Index), Change in Symptom Burden (Edmonton Symptom Assessment Scale), Patient satisfaction with the VR/OS system.

Devices

diagnostic

Body systems

Psychiatry / Mental Health