Study details
Enrolling now
PET Imaging of Vaso-Occlusive Crisis (VOC) in SCD
Enrico Novelli
NCT IDNCT04925492ClinicalTrials.gov data as of Apr 2026
Phase
Phase 1
Target enrollment
20
Study length
about 5.1 years
Ages
18+
Locations
1 site in PA
What this study is about
This trial is testing a new way to see vaso-occlusion, which is blood vessel blockage, in people with sickle cell disease. The goal is to find objective markers for VOC using positron emission tomography (PET). This will help improve patient care by showing when and how VOCs occur, as well as aid future drug research.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive Positron Emission Tomography
- 2.Take Cu-64]-LLP2A
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Standard
How treatment is administered
Treatment Assignment
All receive treatment
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Endpoints
Primary: Association of PET tracer uptake with intensity of pain in VOC
Procedures
imaging