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Study details
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Cefixime Clinical Trial

University of Southern California
NCT IDNCT04958122ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

400

Study length

about 6 years

Ages

18+

Locations

1 site in CA

What this study is about

Researchers are testing cefixime compared to benzathine penicillin G in treating syphilis. The trial will involve 400 adults with early syphilis from sites in the U.S. and Peru, who will receive either cefixime or benzathine penicillin G for 9 months.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take Cefixime 400mg
  • 2.Take benzathine penicillin

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Oral

How treatment is administered

Treatment Assignment
Randomized (Open Label)

You are randomly assigned, but you will know your treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

cefixime, benzathine benzylpenicillin

Drug routes

oral (Oral Capsule)

Body systems

Immune, Infectious