NTS-WBRT in Brain Metastases
Phase 2
41
about 5.9 years
18+
1 site in MA
What this study is about
Researchers are testing the quality of life and symptom burden in adults receiving normal tissue sparing whole brain radiation therapy (NTS-WBRT) along with standard care medication. The trial will last for approximately 2 years.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive NTS-WBRT (normal tissue sparing whole brain radiation therapy)
- 2.Take Memantine
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
memantine
Primary: Change in Patient Reported Quality of Life for NTS-WBRT (normal tissue sparing whole brain radiation therapy), Change in Patient Reported Symptom Burden for NTS-WBRT (normal tissue sparing whole brain radiation therapy)
Secondary: Change in Fatigue between NTS-WBRT+SIB and NTS-WBRT, Intracranial- Progression Free Survival (PFS) between NTS-WBRT+SIB and NTS-WBRT, Number of Participants With Treatment-Related Adverse Events as Assessed by CTCAE Version 5.0, Overall survival (OS) between NTS-WBRT+SIB and NTS-WBRT
radiation