Two Step Haplo With Radiation Conditioning
Phase 2
63
about 11 years
18+
1 site in PA
What this study is about
This trial is testing whether a modified conditioning regimen, using radiation and chemotherapy, can reduce treatment-related mortality (TRM) in adults undergoing hematopoietic stem cell transplant (HSCT) for certain blood cancers. This approach involves two steps: first, lower-intensity treatments are given before the transplant, followed by HSCT to cure the cancer.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive Donor Lymphocyte Infusion
- 2.Receive Total-Body Irradiation
- 3.Take Cyclophosphamide
- +3 more
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
cyclophosphamide (Alkylating chemotherapy; crosslinks DNA strands), fludarabine, melphalan, Immunological Agents (Enzyme Inhibitors), tacrolimus
infusion, intravenous, injection
biopsy, diagnostic, radiation
Oncology