Study details
Enrolling now
Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) Technique
Medical College of Wisconsin
NCT IDNCT05045950ClinicalTrials.gov data as of Apr 2026
Phase
Phase 2
Target enrollment
53
Study length
about 7.5 years
Ages
18+
Locations
2 sites in WI
What this study is about
Researchers are testing a new way to deliver radiation therapy, called PRDR, for brain metastases. Patients will receive WBRT with the PRDR technique along with either memantine or extended release memantine. The trial will last about 2 years.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Receive WBRT utilizing the PRDR technique
- 2.Take Memantine -Twice Daily or Extended Release
Participation Burden
What's physically and logistically required of participants.
Logistics & Travel
In-person visits
Requires travel to a study site
Physical Intervention
Standard
How treatment is administered
Treatment Assignment
All receive treatment
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Drug classes
NERVOUS SYSTEM