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Study details
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Study Assessing Genetically Engineered T-Cells for Viral Infections

M.D. Anderson Cancer Center
NCT IDNCT05101213ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

30

Study length

about 4.1 years

Ages

18+

Locations

1 site in TX

What this study is about

This trial is testing whether a new type of genetically engineered T-cells can help control viral infections in people with cancer who are also immunocompromised. The goal is to determine if these modified cells can safely and effectively target specific viruses, such as adenovirus, BK virus, cytomegalovirus, JC virus, or COVID-19, that cause infections in this population.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Receive Virus-specific Cytotoxic T-lymphocytes

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Feasibility of administering genetically engineered glucocorticoid receptor knock out virus specific cytotoxic T-lymphocyte (CTL) lines, as indicated by Overall Survival

Body systems

Oncology, Infectious