Skip to content
Study details
Enrolling now

Renal Denervation + PVI vs PVI Alone for Persistent AF

University of Rochester
NCT IDNCT05116384ClinicalTrials.gov data as of Apr 2026
Target enrollment

50

Study length

about 2.9 years

Ages

18+

Locations

1 site in NJ

What this study is about

Researchers are testing if adding renal artery denervation to catheter ablation improves long-term outcomes in patients with persistent atrial fibrillation. The trial will compare the effectiveness of RDN plus PVI versus PVI alone, using implantable loop recordings to monitor heart rhythm.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Use catheter ablation
  • 2.Use renal artery denervation

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: Number of subjects with CV hospitalization and/or ER visits, Quality of life in response to ablation

Body systems

Cardiology / Heart