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Study details
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MISSION Trial

University of Massachusetts, Worcester
NCT IDNCT05138614ClinicalTrials.gov data as of Apr 2026
Target enrollment

1,000

Study length

about 4.5 years

Ages

18+

Locations

5 sites in MA

What this study is about

Researchers are testing whether a multi-component team approach (MISSION) improves outcomes for people with opioid use disorder and mental health disorders, compared to medication alone. The trial will last 1634 days and involve 1000 participants.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Medication for Opioid Use Disorder
  • 2.Participate in MISSION Critical Time Intervention
  • 3.Participate in MISSION Dual Recovery Therapy
  • +1 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Chronic pain, Medication Adherence, PTSD symptoms

Secondary: Mortality, Quality Adjusted Life Years (QALYs): quality of life

Body systems

Psychiatry / Mental Health