Gabapentin & Ketamine Trial
Phase 1/2
64
about 4.9 years
21+
1 site in TN
What this study is about
Researchers are testing the safety and best dose of gabapentin and ketamine to prevent or treat pain in people with locally advanced head and neck cancer who are receiving chemotherapy and radiation. The trial will last for about 18 months.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Gabapentin
- 2.Take Ketamine
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
Everyone gets the investigational treatment.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
gabapentin (Modulates calcium channels; used for neuropathic pain and seizures), ketamine (NMDA receptor antagonist; induces dissociative anesthesia and analgesia)
oral (Oral Tablet)
Primary: Count of participants with adverse events (Common Terminology Criteria for Adverse Events Criteria 4.0), Establish the maximum tolerated dose of ketamine in combination with gabapentin (per Common Terminology Criteria for Adverse Events Criteria 4.0)
Oncology