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Study details
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Sleep and Circadian Mechanisms in Hypertension

Oregon Health and Science University
NCT IDNCT05184933ClinicalTrials.gov data as of Apr 2026
Target enrollment

32

Study length

about 5.7 years

Ages

25–64

Locations

1 site in OR

What this study is about

This trial is testing how sleep and the body's natural clock affect blood pressure in people with high blood pressure. Investigators will trial participants with dipping and non-dipping hypertension. Participants will undergo various tests at home and in a lab to understand how sleep and circadian rhythms impact their blood pressure.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.At-home Polysomnography
  • 2.Circadian Protocol
  • 3.Overnight Sleep Trial
  • +2 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Primary: Blood pressure (Circadian and Overnight sleep vs. rested wakefulness trial), Heart rate (Circadian and Overnight sleep vs. rested wakefulness trial), Heart rate variability (Circadian and Overnight sleep vs. rested wakefulness trial), Magnitude of overnight blood pressure dipping (Overnight sleep vs. rested wakefulness trial)

Secondary: Ambulatory blood pressure (Sleep regularization trial), Blood pressure dipping status (Sleep regularization trial)

Body systems

Cardiology / Heart