Clozapine Trial to Prevent Violence in Schizophrenia
Phase 4
280
about 5 years
18–65
7 sites in CA, GA, MD +2
What this study is about
Researchers are testing whether clozapine, a medication, can help prevent violence in people with schizophrenia who have a history of violent acts. Participants will be randomly assigned to receive either clozapine or their usual treatment (TAU). The trial will last for 1809 days.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Clozapine
- 2.Take treatment as usual
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
clozapine (Atypical antipsychotic; blocks dopamine and serotonin (higher efficacy for refractory schizophrenia))
oral (Oral Tablet)
Secondary: Positive symptoms and substance use
Psychiatry / Mental Health