Examining the Effects of Estradiol on Neural and Molecular Response to Reward
Phase 4
103
about 4.7 years
45–55
Female only
1 site in NC
What this study is about
Researchers are testing whether estradiol, a hormone, affects brain function in women experiencing anhedonia (loss of interest), depression, or psychosis. The trial will use imaging techniques to see how estradiol impacts the brain's response to rewards.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Take Matching Placebo Patch
- 2.Take Micronized Progesterone
- 3.Take Raclopride C11
- +1 more
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Hormonal Agents, Stimulant/Replacement/Modifying (Sex Hormones/Modifiers) (Progestational Hormone Receptor Agonists), estradiol
transdermal, oral (Oral Capsule), oral (Oral Tablet)
Secondary: Changes in PO Psychosis Symptoms following Estradiol Administration Using the BPRS
Psychiatry / Mental Health