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Study details
Enrolling now

Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1

Orano Med LLC
NCT IDNCT05283330ClinicalTrials.gov data as of Apr 2026
Phase

Phase 1

Target enrollment

55

Study length

about 4.7 years

Ages

18+

Locations

4 sites in IL, KY, MD +1

What this study is about

This trial is testing the safety and how well a new drug, ²¹²Pb-DOTAM-GRPR1, works in adults with cancer that has returned or spread. The goal is to find out if this treatment can be safely given to people with recurrent or metastatic GRPR-expressing tumors.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.Take ²¹²Pb-DOTAM-GRPR1

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
All receive treatment

Everyone gets the investigational treatment.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Endpoints

Secondary: To assess PK of ²¹²Pb-DOTAM-GRPR1, To assess the safety and tolerability of 203Pb-DOTAM-GRPR1., To assess the safety and tolerability of 212Pb-DOTAM-GRPR1.

Body systems

Oncology