Eccentric Muscle Training, Stimulation, and Biomarkers in SCI
49
about 4.6 years
18–85
1 site in OH
What this study is about
Researchers are testing a new rehabilitation treatment for people with spinal cord injuries (SCI) to improve walking. The trial will measure certain features called biomarkers in blood and spinal fluid to determine the best time to start this training program. This training involves downhill treadmill walking with electrical stimulation, which helps practice walking even if full muscle control hasn't returned.
Simplified from trial records by PatientMatch.
What you may be asked to do
- 1.Downhill Eccentric Treadmill Training with Electrical Stimulation
Participation Burden
What's physically and logistically required of participants.
Requires travel to a study site
How treatment is administered
You may get a placebo/standard care, and you won't know which.
Extracted study details
Pulled from the trial record to show what is being tested and what the study is measuring.
Primary: Change from baseline in electromyography of eccentric acting muscles, Change from baseline in kinematics during weight acceptance: ankle acceleration, Change from baseline in kinematics during weight acceptance: ankle range of motion, Change from baseline in kinematics during weight acceptance: hip acceleration, Change from baseline in kinematics during weight acceptance: hip range of motion, Change from baseline in kinematics during weight acceptance: knee acceleration, Change from baseline in kinematics during weight acceptance: knee range of motion, Change from baseline in kinetics during weight acceptance
Secondary: Change from 12 weeks to 16 weeks in 6 Minute Walk Test (6MWT), Change from 12 weeks to 16 weeks in Neuropathic Pain Symptom Inventory (NPSI) scale, Change from 12 weeks to 16 weeks in Numeric Pain Rating Scale (NPRS), Change from 12 weeks to 16 weeks on Neuromuscular Recovery Scale (NRS) score, Change from baseline in 10 Meter Walk Test, Change from baseline in 6 Minute Walk Test (6MWT), Change from baseline in ASIA Impairment Scale (AIS), Change from baseline in International Standards for Neurological Classification of SCI (ISNCSCI): motor scores
Neurology