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Study details
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CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease

Vanderbilt University Medical Center
NCT IDNCT05422534ClinicalTrials.gov data as of Apr 2026
Phase

Phase 3

Target enrollment

156

Study length

about 4.3 years

Ages

18–75

Locations

2 sites in CA, TN

What this study is about

This trial is testing whether CoQ10, combined with high-intensity interval training (HIIT), can improve mitochondrial function in people with advanced kidney disease. The goal is to see if this combination helps prevent frailty, sarcopenia, and muscle dysfunction.

Simplified from trial records by PatientMatch.

What you may be asked to do

  • 1.CoQ10
  • 2.Participate in HB-HIIT
  • 3.Participate in Observational
  • +1 more

Participation Burden

What's physically and logistically required of participants.

Logistics & Travel
In-person visits

Requires travel to a study site

Physical Intervention
Standard

How treatment is administered

Treatment Assignment
Randomized & Blinded

You may get a placebo/standard care, and you won't know which.

Extracted study details

Pulled from the trial record to show what is being tested and what the study is measuring.

Drug classes

ubidecarenone

Endpoints

Primary: PCr recovery measured by 31 phosphorus magnetic resonance spectroscopy

Secondary: Six minute walk test

Body systems

Renal